Revista de la Facultad de Medicina

Comparison between two antibiotic schemes gentamycin-metronidazole vs. piperacillin- tazobactam and amikacin in treating complicated appendectomies in children

DOI: https://doi.org/10.37345/23045329.v1i20.33

Artículos | Publicado: 2016-06-30

Autores:

  • José Rodrigo Sandoval
  • Héctor Santos Luna

Introduction: A retrospective study was conducted with 60 pediatric patients with diagnosis of complicated appendicitis, in which open appendectomy was performed and treated with metronidazole and gentamycin. Objective: To evaluate efficacy between the combination of a routinely stablished treatment of metronidazole and gentamycin and piperacillin-tazobactam with amikacin in the treatment of complicated appendectomies. Methodology: This retrospective study was conducted in the Pediatric Surgery Unit of the General Hospital San Juan de Dios from January to December 2013. The postoperative complications were assessed of patients who needed a change in antibiotic therapy to piperacillin tazobactam-amikacin. Results: Fifty-six patients (93%) in which the initial antibiotic combination was used recovered without any complications. Four (7%) patients developed intraabdominal collections and needed therapy with piperacillin tazobactam–amikacin with which they resolved the abdominal sepsis. The antibiotic combination gentamycin and metronidazole is still effective in the pediatric population with complicated acute appendicitis in our hospital, leaving the use of piperacillin tazobactam – amikacin as a useful alternative.

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ISSN online 2304-5353 / ISSN printed 2304-5329

 

Cómo citar

Comparison between two antibiotic schemes gentamycin-metronidazole vs. piperacillin- tazobactam and amikacin in treating complicated appendectomies in children. (2016). Revista De La Facultad De Medicina, 1(20). https://doi.org/10.37345/23045329.v1i20.33