Resumen
Introduction: A retrospective study was conducted with 60 pediatric patients with diagnosis of complicated appendicitis, in which open appendectomy was performed and treated with metronidazole and gentamycin. Objective: To evaluate efficacy between the combination of a routinely stablished treatment of metronidazole and gentamycin and piperacillin-tazobactam with amikacin in the treatment of complicated appendectomies. Methodology: This retrospective study was conducted in the Pediatric Surgery Unit of the General Hospital San Juan de Dios from January to December 2013. The postoperative complications were assessed of patients who needed a change in antibiotic therapy to piperacillin tazobactam-amikacin. Results: Fifty-six patients (93%) in which the initial antibiotic combination was used recovered without any complications. Four (7%) patients developed intraabdominal collections and needed therapy with piperacillin tazobactam–amikacin with which they resolved the abdominal sepsis. The antibiotic combination gentamycin and metronidazole is still effective in the pediatric population with complicated acute appendicitis in our hospital, leaving the use of piperacillin tazobactam – amikacin as a useful alternative.
Citas
Sivit C.J., Siegel M.J., Applegate K.E.,et al: When appendicitis is suspected in children. Radio Graphics 2001; 21: 247-262
Brender J.D., Marcuse E.K., Weiss N.S.,et al: Is childhood appendicitis familial?. Am J Dis Child 1985; 139: 338-340
Antibiotics versus placebo for prevention of postoperative infection after appendicectomy. Andersen BR, Kallehave FL, Andersen HK Cochrane Database Syst Rev. 2005
Antibiotics and appendicitis in the pediatric population: an American Pediatric Surgical Association Outcomes and Clinical Trials Committee systematic review. Lee SL, Islam S, Cassidy LD, Abdullah F, Arca MJ, 2010 American Pediatric Surgical Association Outcomes and Clinical Trials Committee. J Pediatr Surg. 2010;45(11):2181.
Weiss A.J., Elixhauser A., Andrew R.M. Characteristics of operating room procedures in U.S.hospitals, 2011. HCUP Statistical Brief #170. Rockville, MD: Agency for Healthcare Research and Quality, 2014.
Slusher J., Bates C.A., Johnson C., et al: Standardization and improvement of care for pediatric patients with perforated appendicitis. J Pediatr Surg 2014; 49: pp. 1020-1025.
Slusher J, Bates C, Johnson C, et al. Standarization and Improvement of Care for Pediatric Patients with Perforated Appendicitis. J Pediatr Surg 2014; 49;1020
Solomon S, Oliver K. Antibiotic Resistance Threats in the United States: Stepping back from the Brink. Amer Fam Phys 2014; 89;938
Adibe O.O., Barnaby K., Dobies J., et al: Postoperative antibiotic therapy for children with perforated appendicitis: long course of intravenous antibiotics versus early conversion to an oral regimen. Am J Surg 2008; 195: pp. 141-143
Safety of a new protocol decreasing antibiotic utilization after laparoscopic appendectomy for perforated appendicitis in children: A prospective observational study. Amita A. Desai, Hanna Alemayehu, George W. Holcomb and Shawn D. St. Peter. J Pediatric Surg, In press.
Chen C., Botello C., Cooper A., et al: Current practice patterns in the treatment of perforated appendicitis in children. J Am Coll Surg 2003; 196: pp. 212-221.
St. Peter S.D., Little D.C., Calkins C.M., et al: A simple and more cost-effective antibiotic regimen for perforated appendicitis. J Pediatr Surg 2006; 41: pp. 1020-1024.
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Copyright (c) 2016 José Rodrigo Sandoval, Héctor Santos Luna

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