Revista de la Facultad de Medicina

Prevalence of atopic dermatitis in asthmatic children

DOI: https://doi.org/10.37345/23045329.v1i29.64

Artículos | Publicado: 2020-12-31

Autores:

  • Ana Sofía Montoya Valladares
    Universidad Francisco Marroquín
  • Edgar Roberto Castillo Sosa
    Instituto de Dermatología y Cirugía de Piel

Introduction: Atopic dermatitis (AD) has been related to different immunologic diseases such as food allergies, asthma or rhinitis; this relationship is known as the “atopic march”. Objective: To determine the prevalence of asthma in pediatric patients, ages 0 to 12 years, with atopic dermatitis in the population of patients evaluated at the INDERMA outpatient clinic in zone 1 of Guatemala City during a period of 6 months. Methodology: This is an observational, cross-sectional, descriptive study in which pediatric patients with a diagnosis of atopic dermatitis were included.  Results: A sample of 316 patients with AD was obtained and a prevalence of asthma was determined to be 19%. It was determined that according to the severity classification of AD, 52% of patients presented with mild disease. Most asthmatic patients presented a moderate form of the disease (27%). AD is more common in infants from 0 to 4 years of age and becomes milder with older age. Conclusion: It was established that the prevalence of asthma in patients with AD at the Institute of Dermatology and Skin Surgery was 19%.

Hill, D.A., Spergel, J.M. The atopic march: critical evidence and clinical relevance. Ann Allergy Asthma Immunol 2018, Feb.; 120(2): 131-137. https://doi.org/10.1016/j.anai.2017.10.037

Spergel, J.M., Paller, A.S. Atopic dermatitis and the atopic march. J Allergy Clin Immunol. 2003, Dec.; 112(6): S118 –S127. https://doi.org/10.1016/j.jaci.2003.09.033

Fernández-Mayoralas, J.M., Martín Caballero, J.M., y García-Marcos, L. Asociación entre dermatitis atópica, rinitis alérgica y asma en escolares de 13 y 14 años. Anales de Pediatría. 2004, Marzo; 60(3): 236-342. https://doi.org/10.1016/S1695-4033(04)78257-0

Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention. Global Guidelines. 2014 Update. http://www.gina.org https://ginasthma.org/wp-content/uploads/2019/01/2014-GINA.pdf

Kulig, M., Bergmann, R., Klettke, U., Wahn, V., Tacke, U., Wahn, U. Natural course of sensitization to food and inhalant allergens during the first 6 years of life. J Allergy Clin Immunol. 1999, June; 103(6): 1173–1179. https://doi.org/10.1016/S0091-6749(99)70195-8

Perkin, M.R., Strachan, D.P., Williams, H.C., Kennedy, C.T., Golding, J., ALSPAC Study Team. Natural history of atopic dermatitis and its relationship to serum total immunoglobulin E in a population-based birth cohort study. Pediatr Allergy Immunol 2004, June; 15(3): 221-229. https://doi.org/10.1111/j.1399-3038.2004.00160.x

Williams, H., Flohr, C. How epidemiology has challenged 3 prevailing concepts about atopic dermatitis. J Allergy Clin Immunol. 2006, July; 118(1): 209-213. https://doi.org/10.1016/j.jaci.2006.04.043

Eichenfield, L.F., Tom, W.L., Berger, T.G., Krol, A., Paller, A.S., Schwarzenberger, K., Bergman, J.N., Chamlin, S.L., Cohen, D.E., Cooper, K.D., Cordoro, K.M., Davis, D.M., Feldman, S.R., Hanifin, J.M., Margolis, D.J., Silverman, R.A., Simpson, E.L., Williams, H.C., Elmets, C.A., Block, J., Harrod, C.G., Smith Begolka, W., Sidbury, R. Guidelines of care for the management of atopic dermatitis : section 2. Management and treatment of atopic dermatitis with topical therapies. J Am Acad Dermatol. 2014, July; 71(1): 116-132. https://doi.org/10.1016/j.jaad.2014.03.023

O’Regan, G.M., Sandilands, A., McLean, W.H., Irvine, A.D. Filaggrin in atopic dermatitis. J Allergy Clin Immunol. 2008, Oct.; 122(4): 689-693. https://doi.org/10.1016/j.jaci.2008.08.002

Riethmuller, C., McAleer, M.A., Koppes, S.A., Abdayem, R., Franz, J., Haftek, M., Campbell, L.E., MacCallum, S.F., McLean, W.H.I., Irvine, A.D., Kezic, S. Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis. J Allergy Clin Immunol. 2015, Dec.; 136(6): 1573-1580. https://doi.org/10.1016/j.jaci.2015.04.042

Williams, H.C. Clinical practice. Atopic dermatitis. N Engl J Med. 2005, June; 352(22): 2314-2324. https://doi.org/10.1056/NEJMcp042803

Bieber, T. Atopic Dermatitis. Ann Dermatol. 2010, May; 22(2): 125-137. https://doi.org/10.5021/ad.2010.22.2.125

Businco, L., Bartolucci, M. Atopic dermatitis and food allergy in Europe--prevalence and risk factors. Allergy. 1998; 53 (Suppl 46): 136-138. https://doi.org/10.1111/j.1398-9995.1998.tb04984.x

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Cómo citar

Prevalence of atopic dermatitis in asthmatic children. (2020). Revista De La Facultad De Medicina, 1(29), 2-9. https://doi.org/10.37345/23045329.v1i29.64