Resumen
Introduction: The use of biomarkers has been suggested to determine the risk of severity progression in patients with COVI-19. Several proven biomarkers such as ferritin, IL-6, white blood cell count, lymphocyte count and platelet count have been identified. Objectives: The aim was to specifically evaluate the relationship between inflammation markers, D-dimer and IL-6, and correlate them with severity and/or mortality. Methodology: The study population was obtained based on the symptoms classification used in the care protocols for patients with COVID-19 infection of the Guatemalan Social Security Institute (IGSS).7 The sample is made up of 623 patients of whom 559 met the inclusion criteria and were considered in this research. Results: There is a statistical difference between both D-dimer levels (p=0.001269) and IL-6 levels (p=0.007) with the mortality prognosis. Discussion: Mortality was 15.6%, and both biomarkers showed to be useful in their prediction. Conclusion: The biomarkers present a statistical relationship with mortality due to COVID -19 infection.
Citas
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Copyright (c) 2021 Christa María Vergara Fernández, Mónica Kiehnle Longo de Longo y Luis Arturo Rodríguez Cifuentes
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