Revista de la Facultad de Medicina

Clinical Description of Pediatric Oncology Patients with Febrile Neutropenia Admitted to the Intensive Care Unit of the National Pediatric Oncology Unit

DOI: https://doi.org/10.37345/23045329.v1i34.84

Artículos científicos | Publicado: 2023-07-28

Autores:

  • Gabriela Marina Gavidia Mayora
    Departamento de Pediatría, Hospital General Infantil de México "Federico Gómez"
  • Amanda Lucía Armendáriz Ortíz
    Facultad de Medicina, Universidad Francisco Marroquín
  • Ricardo Alfredo Mack Rivas
    Unidad Nacional de Oncología Pediátrica

Objective: To describe the clinical characteristics of pediatric oncology patients who were diagnosed with Febrile Neutropenia (NF) admitted for the first time to the Intensive Care Unit (ICU) of the National Pediatric Oncology Unit (UNOP). Methods: This is a descriptive and retrospective study where a total of 211 patients who developed NF and required admission to the ICU, between the years 2017 to 2021, were characterized. Results: The average age was 8 years, 46% were male and 54% female. 72.77% had a severe level of neutropenia and leukemia (81.99%) was the prominent oncologic diagnosis. Within all treatments, 38.39% of the patients were in the induction phase. An associated infectious agent was identified in 33.18%. Gram-negative bacteria were the most frequent causative infectious agent (13.74%). The mean length of stay in the ICU was 6.75 ± 5.79 days. 91.62% of patients did not require mechanical ventilation and the most frequent complication associated with NF was sepsis in 65.88% of cases. Conclusion: Most cases of Febrile Neutropenia are severe, hematological malignancies (ALL and AML) are the most frequent underlying disease for the development of NF and Gram-negative bacteria are the most frequent causative infectious agent. Most patients do not require mechanical ventilation and the most frequently associated complications are Sepsis and Pneumonia

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Facultad de Medicina de la Universidad Francisco Marroquín

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ISSN online 2304-5353 / ISSN printed 2304-5329

 

Cómo citar

Clinical Description of Pediatric Oncology Patients with Febrile Neutropenia Admitted to the Intensive Care Unit of the National Pediatric Oncology Unit. (2023). Revista De La Facultad De Medicina, 1(34), 14-33. https://doi.org/10.37345/23045329.v1i34.84