Revista de la Facultad de Medicina

Dosage of Indocyanine Green to determine the viability of Parathyroid Glands during Thyroid Surgery

DOI: https://doi.org/10.37345/23045329.v1i33.85

Artículos | Publicado: 2022-12-31

Autores:

  • María Jimena Alemán
    Universidad Francisco Marroquín
  • Marco Antonio Peñalonzo
    Centro de Tiroides y Paratiroides

Introduction: The use of light cameras with wavelengths in the near infrared spectrum (NIR) and indocyanine green (IG) angiography allows visualizing and determining the perfusion of the parathyroid glands.  Objectives: To determine the difference in the viability of the parathyroid glands after the application of IG at a dose of 0.01mg/kg versus a dose of 0.02mg/kg of weight.  Methodology: A sample of 20 patients operated on for thyroid pathology was obtained, randomly divided into two groups. During surgery, the number of parathyroid glands identified visually under conventional xenon light and by autofluorescence in the NIR spectrum was recorded. Subsequently, IG was injected intravenously at a dose of 0.01mg/kg in group A and at a dose of 0.02mg/kg in group B. After injection of the dye, the perfusion of the blood cells of the parathyroid glands was measured with a colorimetric scale.   Results: A total of 37 parathyroid glands were identified under conventional xenon light and 42 parathyroid glands by autofluorescence in the NIR spectrum (p=0.4152). The difference between the determination of the viability of the parathyroid glands with conventional xenon light and by angiography after IG injection was not significant (p=0.5714). There was also no difference between group A and B (p=1). Conclusions: There was no difference in determining parathyroid gland perfusion using a 0.01mg/kg IG dose or a 0.02mg/kg dose.

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Facultad de Medicina de la Universidad Francisco Marroquín

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ISSN online 2304-5353 / ISSN printed 2304-5329

 

Cómo citar

Dosage of Indocyanine Green to determine the viability of Parathyroid Glands during Thyroid Surgery. (2022). Revista De La Facultad De Medicina, 1(33), 2-29. https://doi.org/10.37345/23045329.v1i33.85