Resumen
Background: In the last two years, studies have been carried out describing how non-alcoholic hepatic steatosis could be an independent risk marker for the severity of COVID-19. This pro-inflammatory status may contribute to an uncontrolled release of cytokines and predispose to further damage of the lung parenchyma. 11 The radiologic images are a useful tool to classify the severity of the disease. Evaluating the pulmonary lobes through tomography and assigning them established scores, allows treating doctors to establish an appropriate management based on the prognosis of the patients. 5 The objective of the study was to establish the relationship between hepatic steatosis and severe COVID-19 according to tomographic criteria. Methodology: A retrospective cross-sectional descriptive study was carried out in which 956 chest CT scans of patients at the Herrera Llerandi Hospital in Guatemala were evaluated between May 2020 and May 2021. The percentage of involvement of the pulmonary lobes by COVID-19 was evaluated and the Hepatic Attenuation Index (AHI) was obtained to be able to evaluate the presence of hepatic steatosis in order to establish if there is a relationship between both pathologies. Results: 388 CT scans met the inclusion criteria, of which 139 were female patients, 249 males, and the average age was 59.05 years. The prevalence of hepatic steatosis in the sample studied was 27.58%, of which 76.64% were classified as severe COVID-19. The Pearson Correlation test was used with a p value of 0.05 to establish the relationship between hepatic steatosis and severe COVID-19, a positive correlation was obtained with a cor = 0.1114325 indicating that the presence of fatty liver increases the risk 1.2 times of having severe SARS CoV-2 (Odds ratio 1.172, 95% CI 0.6967-1.9733, P = 0.02818). Conclusions: There is a statistically significant positive relationship between hepatic steatosis and severe SARS CoV2 disease.
Citas
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