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Revista de la Facultad de Medicina

Vol. 1 Núm. 35 (2023)

Comparación Clínica y Radiológica de Osteoartritis de mano erosiva vrs Osteoartritis de mano en un centro reumatológico guatemalteco

Artículos científicos
Publicado: 20-11-2023

Resumen

Introducción: Crain, en 1961, identificó presencia de inflamación en pacientes con osteoartritis de mano utilizando para ello el término de osteoartritis inflamatoria, cinco años después Peter et al. Observó alteraciones radiográficas erosivas en algunos casos de osteoartritis de mano. Objetivos: identificar la prevalencia de Osteoartritis erosiva de mano (EHOA), sus factores de riesgo y la sensibilidad de los criterios propuestos por Anandarajah. Metodología: Descriptivo de corte transversal, se comparó 400 pacientes 22 EHOA Y 378 Osteoartritis de manos (HOA) de enero 2021 a febrero 2022 recolectada por revisión de expedientes, los criterios de Anandarajah fueron utilizados.

Resultados: La prevalencia de EHOA es de 5.82% por sexo varía del 4.76 al 1.06% en mujeres y hombres respectivamente, su inicio fue abrupto, el principal factor de riesgo es obesidad con diferencia estadísticamente significativa entre los grupos estudiados, otros factores son sexo femenino, hipertensión, dislipidemia, diabetes mellitus, trabajo manual y trauma articular con valores individuales mas elevados comparados con la HOA. Los criterios diagnósticos estudiados muestran una sensibilidad del 65%

Conclusiones: EHOA presentó mayor componente inflamatorio, inicio abrupto de los síntomas y asociación a factores de riesgo que le predisponen a un estado proinflamatorio crónico; consideramos que la EHOA podría tener una etiopatogenia distinta que la diferencia de la HOA, empero estudios histológicos grandes serian necesarios.

Palabras clave: Osteoartritis, Osteoartritis de mano, Osteoartritis de mano erosiva, incapacidad funcional, obesidad, dolor, erosiones centrales.

 

Citas

  1. Altman, R., Alarcón, G., Appelrouth, et al. The American College of Rheumatology criteria for the classfication and reporting of osteoarthritis of the hand. Arthritis Rheum. 1990, Nov; 33(11): 1601-1610. DOI: 10.1002/art.1780331101 DOI: https://doi.org/10.1002/art.1780331101
  2. Anandarajah, A. Erosive osteoarthritis. Discov Med. 2010, May; 9(48): 468-477. https://pubmed.ncbi.nlm.nih.gov/20515616/
  3. Rillo, O. Actualización en osteoartritis. Separata 2018; 26(1): 60 p. https://www.montpellier.com.ar/Uploads/Separatas/2018%20Osteoartritis.pdf
  4. Vina, E. R. & Kwoh, C. K. Epidemiology of osteoarthritis: literature update. Curr. Opin. Rheumatol. 2018, March; 30(2): 160–167. DOI: 10.1097/BOR.0000000000000479 DOI: https://doi.org/10.1097/BOR.0000000000000479
  5. Cross, M., Smith, E., Hoy, D., et al. The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis, 2014, July; 73(7): 1323–1330. DOI: 10.1136/annrheumdis-2013-204763 DOI: https://doi.org/10.1136/annrheumdis-2013-204763
  6. Creamer, P., Hochberg, M.C. Ostearthritis. The Lancet. 1997, August; 350(9076): 503-509. DOI: https://doi.org/10.1016/S0140-6736(97)07226-7 DOI: https://doi.org/10.1016/S0140-6736(97)07226-7
  7. Schaefer, L. F., McAlindon, T. E., Eaton. The associations between radiographic hand osteoarthritis definitions and hand pain: data from the osteoarthritis initiative. Rheumatology international, 2018, March; 38(3): 403-413. doi: 10.1007/s00296-017-3913-0 DOI: https://doi.org/10.1007/s00296-017-3913-0
  8. Dahaghin, S., Bierma-Zeinstra, S.M., Ginai, A.Z., Pols, H.A., Hazes, J.M., Koes, B.W. Prevalence and pattern of radiographic hand osteoarthritis and association with pain and disability (the Rotterdam study). Ann Rheum Dis. 2005, May; 64(5): 682–687. DOI: 10.1136/ard.2004.023564 DOI: https://doi.org/10.1136/ard.2004.023564
  9. Cardiel, M.H., Rojas-Serrano, J. Community based study to estimate prevalence, burden of illness and help seeking behavior in rheumatic diseases in Mexico City. A COPCORD study. Clin Exp Rheumatol. 2002, Sept.-Oct.; 20(5): 617–624. https://pubmed.ncbi.nlm.nih.gov/12412191/
  10. Peláez-Ballestas, I., Sanín, L.H., Moreno-Montoya, J., et al. Epidemiology of the rheumatic diseases in Mexico. A study of 5 regions based on the COPCORD methodology. J. Rheumatol Suppl. 2011, Jan.; 86: 3–8. DOI: 10.3899/jrheum.100951 DOI: https://doi.org/10.3899/jrheum.100951
  11. Obregón-Ponce, A., Iraheta, I., García-Ferrer, H., Mejía, B., García-Kutzbach, A. Prevalence of musculoskeletal diseases in Guatemala, Central America: the COPCORD study of 2 populations. J. Clin Rheumatol. 2012, June; 18(4): 170–174. DOI: 10.1097/RHU.0b013e3182583803 DOI: https://doi.org/10.1097/RHU.0b013e3182583803
  12. Rodriguez Senna, E., De Barros, A.L.P., Silva, E.O. Prevalence of rheumatic diseases in Brazil: a study using the COPCORD approach. J. Rheumatol. 2004, March; 31(3): 594-597. https://pubmed.ncbi.nlm.nih.gov/14994410/
  13. Reyes-Llerena, G.A., Guibert-Toledano, M., Penedo-Coello, A., et al. Community-based study to estimate prevalence and burden of illness of rheumatic diseases in Cuba: a COPCORD study. J. Clin Rheumatol. 2009, March; 15(2): 51-55. DOI: 10.1097/RHU.0b013e31819b61cb DOI: https://doi.org/10.1097/RHU.0b013e31819b61cb
  14. Crain, D.C. Interphalangeal osteoarthritis characterized by painful, inflammatory episodes resulting in deformity of the proximal and distal articulations. JAMA, 1961, March; 175(12): 1049–1053. doi:10.1001/jama.1961.03040120011003 DOI: https://doi.org/10.1001/jama.1961.03040120011003
  15. Perrotta, F.M., Scriffignano, S., De Socio, A. & Lubrano, E. An Assessment of Hand Erosive Osteoarthritis: Correlation of Radiographic Severity with Clinical, Functional and Laboratory Findings. Rheumatol Ther, 2019, March; 6(1): 125–133. doi: 10.1007/s40744-019-0145-7 DOI: https://doi.org/10.1007/s40744-019-0145-7
  16. Gazeley, D.J., Yeturi, S., Patel, P.J., Rosenthal, A.K. Erosive osteoarthritis: A systematic analysis of definitions used in the literature. Semin Arthritis Rheum. 2017, Feb.; 46(4): 395-403. DOI: 10.1016/j.semarthrit.2016.08.013 DOI: https://doi.org/10.1016/j.semarthrit.2016.08.013
  17. Marshall, M., Watt, F.E., Vincent, T.L., Dziedzic, K. Hand osteoarthritis: clinical phenotypes, molecular mechanisms and disease management. Nat Rev Rheumatol, 2018, Nov.; 14(11): 641–656. DOI: 10.1038/s41584-018-0095-4 DOI: https://doi.org/10.1038/s41584-018-0095-4
  18. Quintero Maritza, Mitrovic Dragoslav et al, Artrosis, Aspectos básicos, fisiopatología, clínica, diagnóstico y tratamiento, capítulo 11, diagnóstico radiológico de la artrosis, primera edición, caracas Venezuela, septiembre 2005
  19. Peter, J.B., Pearson, C.M., Marmor, L. Erosive osteoarthritis of the hands. Arthritis Rheum. 1966, June; 9(3): 365–388. DOI: 10.1002/art.1780090302 DOI: https://doi.org/10.1002/art.1780090302
  20. Punzi, L., Ramonda, R., Sfriso, P. Erosive osteoarthritis. Best Pract Res Clin Rheumatoln 2004, Oct.; 18(5): 739–758. DOI: 10.1016/j.berh.2004.05.010 DOI: https://doi.org/10.1016/j.berh.2004.05.010
  21. Kwok, W.Y., Kloppenburg, M., Rosendaal, F.R., et al. Erosive hand osteoarthritis: its prevalence and clinical impact in the general population and symptomatic hand osteoarthritis. Ann Rheum Dis, 2011, July; 70(7): 1238–1242. DOI: 10.1136/ard.2010.143016 DOI: https://doi.org/10.1136/ard.2010.143016
  22. Kloppenburg, M., Kroon, F.Pb., Blanco, F.J., et al. 2018 update of the EULAR recommendations for the management of hand osteoarthritis. Annals of the Rheumatic Diseases, 2019, Jan.; 78(1): 16-24. DOI: 10.1136/annrheumdis-2018-213826 DOI: https://doi.org/10.1136/annrheumdis-2018-eular.7781
  23. Zhang, Y., Niu, J., Kelly-Hayes, M., Chaisson, C.E., Aliabadi, P., Felson, D.T. Prevalence of Symptomatic Hand Osteoarthritis and Its Impact on Functional Status among the Elderly: The Framingham Study. American Journal of Epidemiology, 2002, Dec.; 156(11): 1021–1027. DOI: 10.1093/aje/kwf141 DOI: https://doi.org/10.1093/aje/kwf141
  24. Siviero, P., Zambon, S., Limongi, F., et al. How hand osteoarthritis, comorbidity and pain interact to determine functional limitation in older people: observations from the European Project on OSteoArthritis study. Arthritis Rheumatol, 2016, Nov.; 68(11): 2662-2670. DOI: 10.1002/art.39757 DOI: https://doi.org/10.1002/art.39757
  25. Damman, W., Liu, R., Kroon, F.P.B., et al. Do Comorbidities Play a Role in Hand Osteoarthritis Disease Burden? Data from the Hand Osteoarthritis in Secondary Care Cohort. J. Rheumatol. 2017, Nov.; 44(11): 1659-1666. DOI: 10.3899/jrheum.170208 DOI: https://doi.org/10.3899/jrheum.170208
  26. Favero, M., Belluzzi, E., Ortolan, A. et al. Erosive hand osteoarthritis: latest findings and outlook. Nat Rev Rheumatol, 2022, March; 18(3): 171–183. DOI: 10.1038/s41584-021-00747-3 DOI: https://doi.org/10.1038/s41584-021-00747-3
  27. Magnusson, K., Hagen, K.B., Østerås, N., et al. Diabetes is associated with increased. hand pain in erosive hand osteoarthritis: data from a population-based study. Arthritis Care Res, 2015, Feb.; 67(2): 187-195. DOI: 10.1002/acr.22460 DOI: https://doi.org/10.1002/acr.22460
  28. Wolf, J.M., Turkiewicz, A., Atroshi, I., Englud, M. Occupational load as a risk factor for clinically relevant base of thumb osteoarthritis. Occupational and Environmental Medicine, 2020, March; 77(3): 168-171. DOI: 10.1136/oemed-2019-106184 DOI: https://doi.org/10.1136/oemed-2019-106184
  29. Rydberg, M., Dahlin, L.B., Gottsäter, A., Nilsson, P.M., Melander, O., Zimmerman, M. High body mass index is associated with increased risk for osteoarthritis of the first carpometacarpal joint during more than 30 years of follow-up. RMD Open, 2020, Oct.; 6(3): e001368. DOI: 10.1136/rmdopen-2020-001368 DOI: https://doi.org/10.1136/rmdopen-2020-001368
  30. Yussuf, E., Neilssen, R.G., Ioan-Facsinay, A., et al. Association between weight or Body Mass Index and hand osteoarthritis: a systematic review. Ann of rheumatic disseases, 2010, April; 69(4): 761-765. DOI: 10.1136/ard.2008.106930 DOI: https://doi.org/10.1136/ard.2008.106930
  31. Jiang, L., Xie, X., Wang, Y., et al. Body mass index and osteoarthritis susceptibility: an updated meta- analysis. International Journal of rheumatic diseases, 2016, Dec.; 19(12): 1244-1254. DOI: 10.1111/1756-185X.12895 DOI: https://doi.org/10.1111/1756-185X.12895
  32. Fioravanti, A., Cheleschi, A., De Palma, A., et al. Can adipokines serum levels be used as biomarkers of hand osteoarthritis? Biomarkers, 2018, May; 23(3): 265-270. DOI: 10.1080/1354750X.2017.1401665 DOI: https://doi.org/10.1080/1354750X.2017.1401665
  33. Allado, E., Wittoek, R, Albuisson, E., et al. Topographical analysis of structural lesions between dominant and non dominant hands in erosive osteoarthritis. Rheumatology International, 2021, March; 41(3): 617-623. DOI: 10.1007/s00296-020-04784-1 DOI: https://doi.org/10.1007/s00296-020-04784-1
  34. Jones, M.E., Davies, M.A.M., Shah, K., et al. The prevalence of hand and wrist osteoarthritis in elite former Cricket and rugby union players. Journal of science and medice in sport, 2019, Aug.; 22(8): 871-875. DOI: 10.1016/j.jsams.2019.03.004 DOI: https://doi.org/10.1016/j.jsams.2019.03.004
  35. Ellulu, M.S., Patimah, I., Khaza'ai, H., Rahmat, A., & Abed, Y. Obesity and inflammation: the linking mechanism and the complications. Archives of medical science : AMS, 2017, June; 13(4): 851–863. DOI: 10.5114/aoms.2016.58928 DOI: https://doi.org/10.5114/aoms.2016.58928
  36. Haugen, I.K., Magnusson, K., Turkiewicz, A., & Englund, M. The Prevalence, Incidence, and Progression of Hand Osteoarthritis in Relation to Body Mass Index, Smoking, and Alcohol Consumption. J. Rheumatol. 2017, Sep; 44(9): 1402-1409. DOI: 10.3899/jrheum.170026 DOI: https://doi.org/10.3899/jrheum.170026
  37. Kwok, W.Y., Kloppenburg, M, Rosendaal, F.R., van Meurs, J.B., Hofman, A., Bierma-Zeinstra, S.M. Erosive hand osteoarthritis: its prevalence and clinical impact in the general population and symptomatic hand osteoarthritis. Ann Rheum Dis. 2011, July; 70(7): 1238-1242. DOI: 10.1136/ard.2010.143016 DOI: https://doi.org/10.1136/ard.2010.143016
  38. Bijsterbosch, J., Watt, I., Meulenbelt, I., Rosendaal, F.R., Huizinga, T.W.J., Kloppenburg M. Clinical burden of erosive hand osteoarthritis and its relationship to nodes. Ann Rheum Dis, 2010, Oct.; 69(10): 1784-1788. DOI: 10.1136/ard.2009.125435 DOI: https://doi.org/10.1136/ard.2009.125435
  39. Pattrick, M., Aldridge, S., Hamilton, E., Manhire, A., Doherty, M. A controlled study of hand function in nodal and erosive osteoarthritis. Ann Rheum Dis., 1989, Dec.; 48(12): 978-982. DOI: 10.1136/ard.48.12.978 DOI: https://doi.org/10.1136/ard.48.12.978
  40. Wittoek, R., Cruyssen, B.V., Verbruggen, G. Predictors of functional impairment and pain in erosive osteoarthritis of the interphalangeal joints: comparison with controlled inflammatory arthritis. Arthritis Rheum, 2012, May; 64(5): 1430-1436. DOI: 10.1002/art.33502 DOI: https://doi.org/10.1002/art.33502
  41. Verbruggen. G., Veys, E.M. Erosive and non-erosive hand osteoarthritis. Use and limitations of two scoring systems. Osteoarthritis and Cartilage, 2000, November; 8: Suppl. A: S45-S54. DOI: 10.1053/joca.2000.0337 DOI: https://doi.org/10.1053/joca.2000.0337
  42. Verbruggen, G., Veys, E.M. Numerical scoring systems for the anatomic evolution of osteoarthritis of the finger joints. Arthritis Rheum, 1996, Feb.; 39(2): 308-320. DOI: 10.1002/art.1780390221 DOI: https://doi.org/10.1002/art.1780390221
  43. Vannini, A., Fusconi, M., Chiara Dall'Aglio, A., Zauli, D. A seroimmunological profile of erosive hand osteoarthritis. Acta Reumatol Port. 2013, Jan-Mar; 38(1): 39-43. https://pubmed.ncbi.nlm.nih.gov/24131910/
  44. Marshall, M., Nicholls, E., Kwok, W.-Y., et al. Erosive osteoarthritis: a more severe form of radiographic hand osteoarthritis rather than a distinct entity? Ann Rheum Dis. 2015, Jan.; 74(1): 136–141. DOI: 10.1136/annrheumdis-2013-203948 DOI: https://doi.org/10.1136/annrheumdis-2013-203948
  45. Garcia-Gil, M., Reyes, C., Ramos, R., et al. Serum Lipid Levels and Risk Of Hand Osteoarthritis: The Chingford Prospective Cohort Study. Scientific Reports, 2017, June; 7: 3147. https://doi.org/10.1038/s41598-017-03317-4 DOI: https://doi.org/10.1038/s41598-017-03317-4
  46. Fioravanti, A., Tenti, S., Pulsatelli, L., & Addimanda, O. Could myeloperoxidase represent a useful biomarker for erosive osteoarthritis of the hand?, Scandinavian Journal of Rheumatology, 2018, Nov.; 47(6): 515-517. DOI: 10.1080/03009742.2017.1386796 DOI: https://doi.org/10.1080/03009742.2017.1386796
  47. Aitken, D., Laslett, L.L., & Pan, F., et al. A Randomised double-blind placebo-controlled crossover trial of HUMira (adalimumab) for erosive hand OsteoaRthritis - the HUMOR Trial. Osteoarthritis and Cartilage, 2018, July: 26(7): 880-887. DOI: 10.1016/j.joca.2018.02.899 DOI: https://doi.org/10.1016/j.joca.2018.02.899

  • Emmanuel Guevara Mejia
    AGAR, UFM
  • Andrea Bran Ordóñez
    Asociación Guatemalteca Anti-Enfermedades Reumáticas (AGAR)
  • Yoell Bautista
    Asociación Guatemalteca Anti-Enfermedades Reumáticas (AGAR)
  • Abraham García-Kutzbach
    Asociación Guatemalteca Anti-Enfermedades Reumáticas (AGAR)
Palabras clave: osteoartritis osteoartritis de mano osteoartritis erosiva discapacidad funcional obesidad dolor

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Cómo citar

Guevara Mejia, E., Bran Ordoñez, A., Bautista, Y. D., & García Kutzbach, A. (2023). Comparación Clínica y Radiológica de Osteoartritis de mano erosiva vrs Osteoartritis de mano en un centro reumatológico guatemalteco. Revista De La Facultad De Medicina, 1(35), 38–51. https://doi.org/10.37345/23045329.v1i35.95