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Revista de la Facultad de Medicina

Vol. 1 No. 34 (2023)

Average parathyroid hormone level in patients with chronic kidney disease stages III to V, National Chronic Renal Patient Care Unit

Artículos científicos
Published: 2023-07-28

Abstract

Despite the prevalence of chronic kidney disease in Guatemala, there are few data on the mineral and bone disorders in chronic kidney disease. An observational cross-sectional study was designed and implemented in a public health institution in Guatemala. Fifty-eight patients with chronic kidney disease in stages III, IV, and V were included to determine serum levels of creatinine, phosphorus, calcium, intact parathormone (PTH), and albumin. The main objective of the study was to determine if the average value of parathyroid hormone differs between stages IIIA, IIIB, IV and V, as well as to stage the degree of bone mineral metabolism alterations in the population studied. Regarding the stages of chronic kidney disease, 50% of patients in stage IIIB; 62% of stage IV and 95% of stage V presented results compatible with secondary hyperparathyroidism. Stage V patients were determined to have statistically different parathyroid hormone values ​​compared with stage IIIA, IIIB, and IV patients with 90% certainty (p= 6.08 x 10⁻⁶). The results of 21% of the patients demonstrated hyperphosphatemia. Hypocalcemia was found in 12% of patients.

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  • Ana María Keilhauer Varona
  • Marco Antonio Peñalonzo Bendfeldt
    Centro de Tiroides y Paratiroides
Palabras clave: chronic kidney disease secondary hyperparathyroidism mineral and bone disorders in chronic kidney disease parathyroid hormone

Revista de la Facultad de Medicina is an Open Access scholarly peer-reviewed journal. It aims to publish clinical research studies and clinical trials contribuiting to enrich the knowledge and development of the Medical Science. The journal is published semi-annualy by the Faculty of Medicine of Francisco Marroquin university. 

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How to Cite

Keilhauer Varona, A. M., & Peñalonzo Bendfeldt, M. A. (2023). Average parathyroid hormone level in patients with chronic kidney disease stages III to V, National Chronic Renal Patient Care Unit. Revista De La Facultad De Medicina, 1(34), 34–48. https://doi.org/10.37345/23045329.v1i34.94