Resumen
A pesar de la prevalencia de enfermedad renal crónica en Guatemala, existen pocos datos sobre los trastornos minerales y del hueso propios de la enfermedad renal crónica. Se diseñó e implementó un estudio transversal observacional en una institución de salud pública de Guatemala. Se incluyeron cincuenta y ocho pacientes con enfermedad renal crónica en estadios III, IV, y V para determinar niveles séricos de creatinina, fósforo, calcio, parathormona (HPT) intacta y albúmina. El objetivo principal del estudio fue determinar si el valor promedio de hormona paratiroidea difiere entre estadios IIIA, IIIB, IV y V, así como estadificar el grado de alteraciones del metabolismo óseo mineral en la población estudiada. Con respecto a los estadios de enfermedad renal crónica, 50% de los pacientes en estadio IIIB; 62% de los estadio IV, y 95% de los estadio V presentaron resultados compatibles con hiperparatiroidismo secundario. En conclusión, se determinó que pacientes en estadio V tenían valores de hormona paratiroidea estadísticamente diferentes, comparado con pacientes en estadios IIIA, IIIB, y IV con un 90% de certeza (p= 6.08 x 10-6)
Citas
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